Dibucaine HCl

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Chemical Structure| 61-12-1 同义名 : 盐酸地布卡因 ;Cinchocaine hydrochloride; Cinchocaine HCl; Dibucaine hydrochloride
CAS号 : 61-12-1
货号 : A206913
分子式 : C20H30ClN3O2
纯度 : 99+%
分子量 : 379.92
MDL号 : MFCD00012735
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(276.37 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(263.21 mM)，配合低频超声助溶
生物活性
靶点

  • Sodium Channel
描述 Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.63mL

0.53mL

0.26mL

13.16mL

2.63mL

1.32mL

26.32mL

5.26mL

2.63mL
参考文献

[1]Yamadori Y, Oiso N, et al. Allergic contact dermatitis from dibucaine hydrochloride, chlorpheniramine maleate, and naphazoline hydrochloride in an over-the-counter topical antiseptic. Contact Dermatitis. 2009 Jul;61(1):52-3.

[2]Hayashi K, Kawachi S, Saida T. Allergic contact dermatitis due to both chlorpheniramine maleate and dibucaine hydrochloride in an over-the-counter medicament. Contact Dermatitis. 2001 Jan;44(1):38-9.