Asymmetric dimethylarginine

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Chemical Structure| 30315-93-6 同义名 : NG,NG-Dimethylarginine; ADMA; NG,NG-dimethyl-L-Arginine
CAS号 : 30315-93-6
货号 : A203396
分子式 : C8H18N4O2
纯度 : 95%
分子量 : 202.25
MDL号 : MFCD00038406
存储条件:

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(519.15 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 100 mg/mL(494.43 mM),调节pH至2-3

生物活性
描述 Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS) and serves as a marker of endothelial dysfunction in a variety of pathological states. Asymmetric dimethylarginine is elevated in HIV-1 infection[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.94mL

0.99mL

0.49mL

24.72mL

4.94mL

2.47mL

49.44mL

9.89mL

4.94mL

参考文献

[1]Hudson CL, et al. The cardiovascular risk marker asymmetric dimethylarginine is elevated in asymptomatic, untreated HIV-1 infection and correlates with markers of immune activation and disease progression. Ann Clin Biochem. 2014 Sep;51(Pt 5):568-75.