UTL-5g
产品说明书
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同义名 : | GBL-5g |
| CAS号 : | 646530-37-2 | |
| 货号 : | A180991 | |
| 分子式 : | C11H8Cl2N2O2 | |
| 纯度 : | 97% | |
| 分子量 : | 271.1 | |
| MDL号 : | MFCD08724989 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(387.31 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | UTL-5g, also known as GBL-5g, is an anti-inflammatory TNF-α inhibitor with chemoprotective and hepatic radioprotective effects. UTL-5g reduces cisplatin-induced hepatotoxicity, nephrotoxicity, and myelotoxicity through inhibition of TNF-α, among other factors[1][2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.69mL 0.74mL 0.37mL |
18.44mL 3.69mL 1.84mL |
36.89mL 7.38mL 3.69mL |
| 参考文献 |
|---|
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[1]Stephen Brown, et al. UTL-5g Lowers Levels of TGF-β and TNF-α Elevated by Lung Irradiation |