Phloracetophenone

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Chemical Structure| 480-66-0 同义名 : 2',4',6'-三羟基苯乙酮 ;2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone; THAP Monohydrate
CAS号 : 480-66-0
货号 : A177587
分子式 : C8H8O4
纯度 : 98%
分子量 : 168.15
MDL号 : MFCD00002287
存储条件:

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 25 mg/mL(148.68 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 2 mg/mL(11.89 mM),配合低频超声助溶

动物实验配方:
生物活性
描述 2',4',6'-Trihydroxyacetophenone, a natural product isolated and purified from the barks of Albizia julibrissin, has antiobesity and hypolipidemic effects and may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipase activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.95mL

1.19mL

0.59mL

29.74mL

5.95mL

2.97mL

59.47mL

11.89mL

5.95mL

参考文献

[1]Ferreira EA, Gris EF, et al. The 2',4',6'-trihydroxyacetophenone isolated from Myrcia multiflora has antiobesity and mixed hypolipidemic effects with the reduction of lipid intestinal absorption. Planta Med. 2011 Sep;77(14):1569-74.

[2]Hsu NY, Yang WB, et al. Matrix-assisted laser desorption/ionization mass spectrometry of polysaccharides with 2',4',6'-trihydroxyacetophenone as matrix. Rapid Commun Mass Spectrom. 2007;21(13):2137-46.