CTX-0294885

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Chemical Structure| 1439934-41-4 同义名 : -
CAS号 : 1439934-41-4
货号 : A173517
分子式 : C22H24ClN7O
纯度 : 99%+
分子量 : 437.93
MDL号 : MFCD28137930
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(239.77 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 CTX-0294885 is a broad-spectrum kinase inhibitor capable of targeting 235 kinases in MDA-MB-231 cells, including all members of the AKT family, marking its utility in dissecting kinome signaling pathways for the study of diseases such as inflammation, diabetes, and cancer.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.28mL

0.46mL

0.23mL

11.42mL

2.28mL

1.14mL

22.83mL

4.57mL

2.28mL
参考文献

[1]Zhang L, et al. Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling. J Proteome Res. 2013 Jul 5;12(7):3104-16.