DS12881479

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Chemical Structure| 2373065-59-7 同义名 : -
CAS号 : 2373065-59-7
货号 : A1676519
分子式 : C16H19N3OS
纯度 : 99%+
分子量 : 301.41
MDL号 : N/A
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(829.44 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 DS12881479, a potent and selective Mnk1 inhibitor, displays an IC50 value of 21 nM and is applicable in cancer research [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.32mL

0.66mL

0.33mL

16.59mL

3.32mL

1.66mL

33.18mL

6.64mL

3.32mL
参考文献

[1]Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57(3):1339-46.