AN2
产品说明书
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同义名 : | LC3-mHTT-IN-AN2 |
| CAS号 : | 7758-73-8 | |
| 货号 : | A164604 | |
| 分子式 : | C15H10O4 | |
| 纯度 : | 95% | |
| 分子量 : | 254.24 | |
| MDL号 : | MFCD01078551 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 120 mg/mL(472 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | LC3-mHTT-IN-AN2, a linker compound for mHTT-LC3, engages with mutant huntingtin protein (mHTT) and LC3B, but does not interact with wild-type HTT or unrelated control proteins. This compound selectively lowers mHTT levels in cultured neurons from Huntington disease (HD) mice in an allele-specific fashion[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.93mL 0.79mL 0.39mL |
19.67mL 3.93mL 1.97mL |
39.33mL 7.87mL 3.93mL |
| 参考文献 |
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