D-Luciferin potassium

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Chemical Structure| 115144-35-9 同义名 : D-虫萤光素钾盐 ;Firefly luciferin potassium; Beetle Luciferin potassium; D-Luciferin (potassium salt); D-Luciferin Potassium Salt; D-(-)-Luciferin potassium
CAS号 : 115144-35-9
货号 : A162108
分子式 : C11H7KN2O3S2
纯度 : 97%
分子量 : 318.41
MDL号 : MFCD00044928
存储条件：

Pure form Inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 25 mg/mL(78.51 mM)，配合低频超声助溶
生物活性
描述 D-Luciferin potassium salt is the water-soluble potassium salt form of D-Luciferin. D-Luciferin is the substrate for the enzyme Firefly Luciferase. It can produce bioluminescence through oxidation by the enzyme luciferase. The typical emission spectrum for luciferase is in the yellow-green region (550–570 nm), with a peak at 562 nm at basic media (pH~7.5–7.8)[1]. For D-Luciferin potassium salt possesses water solubility, it is usually in in vivo bioluminescence imaging[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.14mL

0.63mL

0.31mL

15.70mL

3.14mL

1.57mL

31.41mL

6.28mL

3.14mL
参考文献

[1]Marques SM, Esteves da Silva JC. Firefly bioluminescence: a mechanistic approach of luciferase catalyzed reactions. IUBMB Life. 2009 Jan;61(1):6-17.

[2] Henriques C, Henriques-Pons A, Meuser-Batista M, Ribeiro AS, de Souza W. In vivo imaging of mice infected with bioluminescent Trypanosoma cruzi unveils novel sites of infection. Parasit Vectors. 2014 Mar 3;7:89.

[3] Liao JB, Ovenell KJ, Curtis EE, et al. Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer. J Immunother Cancer. 2015;3:16.