(S)-ZLc002

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Chemical Structure| 308277-46-5 同义名 : ZLc002
CAS号 : 308277-46-5
货号 : A1615356
分子式 : C10H17NO5
纯度 : 98%+
分子量 : 231.25
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(454.06 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 (S)-ZLc002, the S-enantiomer of ZLc-002, selectively inhibits nNOS-Capon coupling and reduces inflammatory nociception as well as chemotherapy-induced neuropathic pain[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.32mL

0.86mL

0.43mL

21.62mL

4.32mL

2.16mL

43.24mL

8.65mL

4.32mL
参考文献

[1]Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099.