FAK-IN-7

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Chemical Structure| 19948-85-7 同义名 : -
CAS号 : 19948-85-7
货号 : A1598840
分子式 : C16H13N3OS
纯度 : 95%
分子量 : 295.36
MDL号 : MFCD00660411
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 9 mg/mL(30.47 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 FAK-IN-7, possessing an IC50 of 11.72 µM, is a focal adhesion kinase (FAK) inhibitor with notable anti-proliferative activity, suitable for cancer research [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.39mL

0.68mL

0.34mL

16.93mL

3.39mL

1.69mL

33.86mL

6.77mL

3.39mL
参考文献

[1]Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.