LY3537982
产品说明书
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同义名 : | Olomorasib; KRAS G12C inhibitor 19 |
| CAS号 : | 2649788-46-3 | |
| 货号 : | A1553137 | |
| 分子式 : | C25H19ClF2N4O3S | |
| 纯度 : | 99%+ | |
| 分子量 : | 528.96 | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 120 mg/mL(226.86 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | KRAS G12C inhibitor 19 is a potent inhibitor targeting KRAS G12C. It notably suppresses tumor growth (extracted from patent WO2021118877A1)[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.89mL 0.38mL 0.19mL |
9.45mL 1.89mL 0.95mL |
18.91mL 3.78mL 1.89mL |
| 参考文献 |
|---|
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[1]Serge Louis Boulet, et al. Kras g12c inhibitors. Patent WO2021118877A1. |