23-Hydroxybetulinic acid

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Chemical Structure| 85999-40-2 同义名 : 23-羟基白桦酸 ;Anemosapogenin; 23-HBA
CAS号 : 85999-40-2
货号 : A146676
分子式 : C30H48O4
纯度 : 98%
分子量 : 472.7
MDL号 : MFCD28126999
存储条件：

Pure form Inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(222.13 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 23-hydroxybetulinic acid is one of the bioactive components responsible for its anticancer activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.12mL

0.42mL

0.21mL

10.58mL

2.12mL

1.06mL

21.16mL

4.23mL

2.12mL
参考文献

[1]Liu M, Zhao X, et al. Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid. Pharm Biol. 2015 Jan;53(1):1-9.

[2]Zhang DM, Shu C, et al. BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo. Mol Pharm. 2012 Nov 5;9(11):3147-59.