MP07-66

产品说明书

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Chemical Structure| 1938056-90-6 同义名 : -
CAS号 : 1938056-90-6
货号 : A1461849
分子式 : C19H33NO3
纯度 : 99%+
分子量 : 323.47
MDL号 : N/A
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(772.87 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 MP07-6 is a FTY720 analogue, but it has no immunosuppressive effect. It shows good anti-tumor effect in chronic lymphoblastic leukemia by destroying SET-PP2A complex and causing PP2A reactivation.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.09mL

0.62mL

0.31mL

15.46mL

3.09mL

1.55mL

30.91mL

6.18mL

3.09mL
参考文献

[1]Zonta F, et al. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. Blood. 2015;125(24):3747-3755.