Ampicillin Trihydrate

产品说明书

Print
Chemical Structure| 7177-48-2 同义名 : 氨苄青霉素，三水 ;D-(-)-α-Aminobenzylpenicillin trihydrate; Ukapen; Polycillin; Pentrexyl; Omnipen; KS-R1; Aminobenzyl Penicillin; Amcill; Aminobenzylpenicillin trihydrate
CAS号 : 7177-48-2
货号 : A142546
分子式 : C16H25N3O7S
纯度 : 99%
分子量 : 403.45
MDL号 : MFCD00072036
存储条件：

Pure form Keep in dark place,Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 4 mg/mL(9.91 mM)，配合低频超声，并水浴加热至45℃助溶
生物活性
描述 Ampicillin is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01511107 Acute Otitis Media Phase 2 Terminated(The primary objecti... 展开 >>ve of the study was met.) 收起 << - United States, Kentucky ... 展开 >> Kentucky Pediatric/Adult Research Bardstown, Kentucky, United States, 40004 United States, Pennsylvania Children's Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania, United States, 15224 收起 <<
NCT01892488 Chronic Obstructive Pulmonary ... 展开 >>Disease (COPD) 收起 << Phase 4 Recruiting September 2018 Germany ... 展开 >> Universitätsklinikum Aachen Recruiting Aachen, Germany HELIOS Klinikum Emil von Behring Berlin Recruiting Berlin, Germany Universitätsklinikum Dresden Recruiting Dresden, Germany Universitätsmedizin Greifswald Recruiting Greifswald, Germany Medizinische Hochschule Hannover Recruiting Hannover, Germany Principal Investigator: Tobias Welte, Prof. Dr.          Lungenfachklinik Immenhausen Recruiting Immenhausen, Germany Universitätsklinikum Jena Recruiting Jena, Germany Universitätsklinikum Schleswig-Holstein Campus Lübeck Recruiting Lübeck, Germany Brüderkrankenhaus St. Josef Paderborn Recruiting Paderborn, Germany Diakoniekrankenhaus Rotenburg Recruiting Rotenburg, Germany Krankenhaus Bethanien Solingen Recruiting Solingen, Germany 收起 <<
NCT01511107 - Terminated(The primary objecti... 展开 >>ve of the study was met.) 收起 << - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.39mL

2.48mL

1.24mL

24.79mL

4.96mL

2.48mL
参考文献

[1]Lacy MK, Lu W, et al. Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection. Antimicrob Agents Chemother. 1999 Mar;43(3):672-7.

[2]Dunnick JK, Elwell MR. Toxicity studies of amphetamine sulfate, ampicillin trihydrate, codeine, 8-methoxypsoralen, alpha-methyldopa, penicillin VK and propantheline bromide in rats and mice. Toxicology. 1989 Jun 1;56(2):123-36.