IMT1B
产品说明书
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同义名 : | LDC203974 |
| CAS号 : | 2304621-06-3 | |
| 货号 : | A1375194 | |
| 分子式 : | C24H21ClFNO6 | |
| 纯度 : | 97% | |
| 分子量 : | 473.88 | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 250 mg/mL(527.56 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | IMT1B (LDC203974) is an orally active, noncompetitive, and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT), leading to the inhibition of mitochondrial DNA (mtDNA) expression. IMT1B exhibits anti-tumor effects [1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.11mL 0.42mL 0.21mL |
10.55mL 2.11mL 1.06mL |
21.10mL 4.22mL 2.11mL |
| 参考文献 |
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