[8]-Shogaol

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Chemical Structure| 36700-45-5 同义名 : 8-Shogaol
CAS号 : 36700-45-5
货号 : A1371156
分子式 : C19H28O3
纯度 : 99%+
分子量 : 304.42
MDL号 : MFCD21333718
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(344.91 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 8-Shogaol, a natural product isolated and purified from the rhizomes of Zingber officinale Rosc., can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.28mL

0.66mL

0.33mL

16.42mL

3.28mL

1.64mL

32.85mL

6.57mL

3.28mL
参考文献

[1]Chen H, Soroka DN, et al. Characterization of thiol-conjugated metabolites of ginger components shogaols in mouse and human urine and modulation of the glutathione levels in cancer cells by [6] -shogaol. Mol Nutr Food Res. 2013 Mar;57(3):447-58.

[2]Shieh PC, Chen YO, et al. Induction of apoptosis by [8] -shogaol via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells. J Agric Food Chem. 2010 Mar 24;58(6):3847-54.