Thalidomide-O-amido-PEG3-C2-NH2 HCl
产品说明书
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同义名 : | - |
| CAS号 : | 2245697-84-9 | |
| 货号 : | A1363874 | |
| 分子式 : | C23H31ClN4O9 | |
| 纯度 : | 95% | |
| 分子量 : | 542.97 | |
| MDL号 : | MFCD31656717 | |
| 存储条件： |
Pure form Sealed in dry,Store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 120 mg/mL(221.01 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 100 mg/mL(184.17 mM)，配合低频超声助溶 |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Thalidomide-O-amido-PEG3-C2-NH2 HCl is a molecule used for the synthesis of PROTAC molecules and consists of E3 ligand and liner[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.84mL 0.37mL 0.18mL |
9.21mL 1.84mL 0.92mL |
18.42mL 3.68mL 1.84mL |
| 参考文献 |
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[1]Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1. |