2-Thenoyltrifluoroacetone

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Chemical Structure| 326-91-0 同义名 : HTTA; TTA; Thenoyltrifluoroacetone; NSC 405706; NSC 405705; NSC 405704; NSC 405703; NSC 405702; NSC 66544; TTFA
CAS号 : 326-91-0
货号 : A135642
分子式 : C8H5F3O2S
纯度 : 97%
分子量 : 222.18
MDL号 : MFCD00005445
存储条件:

Pure form Keep in dark place, sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(472.58 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 2-Thenoyltrifluoroacetone serves as a chelating agent and is employed in the complexation of various metal ions, including Mn(II), Co(III), and Ni(II). This compound exhibits antitubercular and cytotoxic properties, inhibits mitochondrial electron flux, and is used in studying endothelial cell dysfunction. Additionally, the copper (II) complex of 2-Thenoyltrifluoroacetone shows anticancer effects against K562 cells[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.50mL

0.90mL

0.45mL

22.50mL

4.50mL

2.25mL

45.01mL

9.00mL

4.50mL

参考文献

[1]Masoudi Khoram, et al. Comparative evaluation of the efficiency of batch and flow electrochemical cells in the synthesis of a new derivative of 2-thenoyltrifluoroacetone. Journal of Electroanalytical Chemistry. 2020;879.