STAD 2

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Chemical Structure| 1542100-77-5 同义名 : -
CAS号 : 1542100-77-5
货号 : A1340656
分子式 : C102H182N24O22
纯度 : 98%
分子量 : 2096.68
MDL号 : N/A
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(50.08 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

0.48mL

0.10mL

0.05mL

2.38mL

0.48mL

0.24mL

4.77mL

0.95mL

0.48mL
参考文献

[1]Wang Y, Ho TG, Bertinetti D, et al. Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides [published correction appears in ACS Chem Biol. 2014 Jun 20;9(6):1386]. ACS Chem Biol. 2014;9(3):635-642. doi:10.1021/cb400900r

[2]Flaherty BR, Wang Y, Trope EC, et al. The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism. PLoS One. 2015;10(5):e0129239. Published 2015 May 26. doi:10.1371/journal.pone.0129239

[3]Bendzunas NG, Dörfler S, Autenrieth K, et al. Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2. Bioorg Med Chem. 2018;26(6):1174-1178. doi:10.1016/j.bmc.2018.02.001