Gomisin G

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Chemical Structure| 62956-48-3 同义名 : -
CAS号 : 62956-48-3
货号 : A133513
分子式 : C30H32O9
纯度 : 99%
分子量 : 536.57
MDL号 : MFCD21333382
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(93.18 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Gomisin G is an ethanolic extract of the stems of Kadsura interior and exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 mg/mL and 300, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.86mL

0.37mL

0.19mL

9.32mL

1.86mL

0.93mL

18.64mL

3.73mL

1.86mL
参考文献

[1]Chen DF, Zhang SX, et al. Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg Med Chem. 1997 Aug;5(8):1715-23.

[2]Ikeya Y, Taguchi H, et al. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem Pharm Bull (Tokyo). 1979 Jun;27(6):1383-94.