Aminothiazole

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Chemical Structure| 96-50-4 同义名 : 氨噻唑 ;2-Aminothiazole; 2-Thiazolylamine; NSC 1900; Basedol
CAS号 : 96-50-4
货号 : A128996
分子式 : C3H4N2S
纯度 : 98%
分子量 : 100.14
MDL号 : MFCD00005325
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(499.29 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(998.58 mM)
动物实验配方：
生物活性
描述 Aminothiazole (2-Aminothiazole), a common heterocyclic amine, serves as a precursor in crafting biologically active compounds such as sulfur agents, biocides, fungicides, antibiotics, dyes, and chemical accelerators[1][2].
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02273219 Uveal Melanoma Phase 1 Active, not recruiting December 2018 United States, Florida ... 展开 >> Bascom Palmer Eye Institute of University Of Miami Medical Center Miami, Florida, United States, 33136 United States, New York Columbia University Medical Center New York, New York, United States, 10032 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 收起 <<
NCT02145312 Recurrent or Metastatic Squamo... 展开 >>us Cell Carcinoma of Head and Neck 收起 << Phase 2 Recruiting May 2019 Korea, Republic of ... 展开 >> Yonsei Cancer Center at Yonsei University Medical Center Recruiting Seoul, Korea, Republic of, 03722 Contact: Byung Chul Cho, M.D., Ph.D.    82-2-2228-0880    CBC1971@yuhs.ac 收起 <<
NCT03292250 HNSCC Head an... 展开 >>d Neck Neoplasms 收起 << Phase 2 Recruiting December 31, 2020 Korea, Republic of ... 展开 >> Seoul National University Hospital Recruiting Seoul, Korea, Republic of, 110-744 Contact: Bhumsuk Keam, MD    82-2-2072-7215    bhumsuk@snu.ac.kr    Principal Investigator: Hye Ryun Kim          Principal Investigator: Hwan Jung Yun          Principal Investigator: Myung-Ju Ahn          Principal Investigator: Sung Bae Kim          Principal Investigator: Hyun Chang          Principal Investigator: Sang Hoon Chun          Principal Investigator: InSook Woo          Principal Investigator: Yoon Ho Ko          Principal Investigator: Ji Hyung Hong          Principal Investigator: jung hye kwon          Principal Investigator: Heui-june Ahn          Principal Investigator: Yun Gyoo Lee          Principal Investigator: Keonuk Park          Principal Investigator: Eun Joo Kang          Principal Investigator: Seong-Hoon Shin          Principal Investigator: Tak Yun          Principal Investigator: Yoon Hee Choi          Principal Investigator: Keun-Wook Lee          Principal Investigator: Joo-Hang Kim          Principal Investigator: JinSoo Kim          Principal Investigator: Sang-Cheol Lee          Principal Investigator: Hyun Woo Lee          Principal Investigator: Min Kyoung Kim          Principal Investigator: Hyeok Shim          Principal Investigator: Seung taek Lim          Principal Investigator: Kyoung Eun Lee          Principal Investigator: Moon Young Choi          Principal Investigator: Joohan Lim          Principal Investigator: In Gyu Hwang          Principal Investigator: Hyo Jung Kim          Principal Investigator: Jun Eul Hwang          Principal Investigator: Ho Jung An          Principal Investigator: So Yeon Oh          Principal Investigator: Sang-Gon Park          Principal Investigator: Hee Kyoung Ahn          Principal Investigator: Sun Min Lim 收起 <<
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

9.99mL

2.00mL

1.00mL

49.93mL

9.99mL

4.99mL

99.86mL

19.97mL

9.99mL
参考文献

[1]Gallardo-Godoy A, et al. 2-Aminothiazoles as therapeutic leads for prion diseases. J Med Chem. 2011 Feb 24;54(4):1010-21.

[2]Khalifa ME, et, al. Recent Developments and Biological Activities of 2-Aminothiazole Derivatives. Acta Chim Slov. 2018 Mar;65(1):1-22.

[3]Ran K, et, al. Identification of novel 2-aminothiazole conjugated nitrofuran as antitubercular and antibacterial agents. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3669-74.