ADU-S100

产品说明书

Print
Chemical Structure| 1638241-89-0 同义名 : Ml rr-s2 cda; MIW815; 2'3'-c-di-AM(PS)2(Rp,Rp)
CAS号 : 1638241-89-0
货号 : A127865
分子式 : C20H24N10O10P2S2
纯度 : 98%
分子量 : 690.54
MDL号 : MFCD28900737
存储条件:

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 20 mg/mL(28.96 mM),配合低频超声助溶

生物活性
描述 ML RR-S2 CDA is a highly active cyclic-di-nucleotide immune stimulators that activate DCs via the cytoplamtic receptor STING (Stimulator of Interferon Genes).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.45mL

0.29mL

0.14mL

7.24mL

1.45mL

0.72mL

14.48mL

2.90mL

1.45mL

参考文献

[1]Corrales L, Glickman LH, et al. Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity. Cell Rep. 2015 May 19;11(7):1018-30.