Ralaniten triacetate
产品说明书
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同义名 : | EPI-506 |
| CAS号 : | 1637573-04-6 | |
| 货号 : | A1275527 | |
| 分子式 : | C27H33ClO8 | |
| 纯度 : | 97% | |
| 分子量 : | 521.0 | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(201.54 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is the first orally active inhibitor targeting the androgen receptor (AR) N-terminal domain (NTD). It is effective against both the full-length AR and variants associated with resistance, such as AR-v7[1][2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.92mL 0.38mL 0.19mL |
9.60mL 1.92mL 0.96mL |
19.19mL 3.84mL 1.92mL |
| 参考文献 |
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