Flupyradifurone

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Chemical Structure| 951659-40-8 同义名 : -
CAS号 : 951659-40-8
货号 : A1256938
分子式 : C12H11ClF2N2O2
纯度 : 97%
分子量 : 288.68
MDL号 : MFCD22373627
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(363.73 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Flupyradifurone acts as a systemic nAChR agonist disrupting signal transduction in the central nervous systems of sucking pests and is used as a butenolide insecticide[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.46mL

0.69mL

0.35mL

17.32mL

3.46mL

1.73mL

34.64mL

6.93mL

3.46mL
参考文献

[1]Yi Guo, et al. The Effects of Exposure to Flupyradifurone on Survival, Development, and Foraging Activity of Honey Bees (Apis mellifera L.) under Field Conditions. Insects. 2021 Apr 16;12(4):357.

[2]Mark Montgomery, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators. J Med Chem. 2022 Jan 5.

[3]Yizhi Feng, et al. Determination, residue analysis, dietary risk assessment, and processing of flupyradifurone and its metabolites in pepper under field conditions using LC-MS/MS. Biomed Chromatogr. 2022 Jan 3;e5312.