Fluorescein-DBCO

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Chemical Structure| 2054339-00-1 同义名 : -
CAS号 : 2054339-00-1
货号 : A1251452
分子式 : C39H27N3O6S
纯度 : 98%
分子量 : 665.71
MDL号 : MFCD30527400
存储条件：

Pure form Inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Fluorescein-DBCO serves as a non-cleavable linker in the synthesis of antibody-drug conjugates (ADCs) [1]. Fluorescein-DBCO functions as a click chemistry reagent, featuring a DBCO group capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing Azide groups.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.50mL

0.30mL

0.15mL

7.51mL

1.50mL

0.75mL

15.02mL

3.00mL

1.50mL
参考文献

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.