Casein kinase 1δ-IN-1

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Chemical Structure| 851871-94-8 同义名 : -
CAS号 : 851871-94-8
货号 : A1229446
分子式 : C11H7N3OS
纯度 : 99%+
分子量 : 229.26
MDL号 : MFCD06387193
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 40 mg/mL(174.48 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Casein kinase 1δ-IN-1, an inhibitor of casein kinase 1 delta (CK1δ), exhibits inhibition exceeding 5%, suitable for neurodegenerative disorder research, including Alzheimer's disease [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.36mL

0.87mL

0.44mL

21.81mL

4.36mL

2.18mL

43.62mL

8.72mL

4.36mL
参考文献

[1]Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.