Tasisulam

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Chemical Structure| 519055-62-0 同义名 : 他司磺胺 ;LY 573636
CAS号 : 519055-62-0
货号 : A122315
分子式 : C11H6BrCl2NO3S2
纯度 : 99%+
分子量 : 415.11
MDL号 : N/A
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(602.25 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Tasisulam, an anticancer agent, induces apoptosis via the intrinsic pathway, resulting in cytochrome c release and caspase-dependent cell death. It also inhibits mitotic progression and induces vascular normalization [1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.41mL

0.48mL

0.24mL

12.05mL

2.41mL

1.20mL

24.09mL

4.82mL

2.41mL
参考文献

[1]Meier T, et al. Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization. Mol Cancer Ther. 2011 Nov;10(11):2168-78.