MitoPQ

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Chemical Structure| 1821370-28-8 同义名 : MitoParaquat
CAS号 : 1821370-28-8
货号 : A1210808
分子式 : C39H46I3N2P
纯度 : 97%
分子量 : 954.48
MDL号 : N/A
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(36.67 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 50 mg/mL(52.38 mM)，配合低频超声助溶
生物活性
描述 MitoPQ acts as a mitochondria-focused redox cycler, generating superoxide through redox cycling at complex I's flavin site, thus selectively boosting superoxide levels within mitochondria. It is applicable in studies of antioxidants[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.05mL

0.21mL

0.10mL

5.24mL

1.05mL

0.52mL

10.48mL

2.10mL

1.05mL
参考文献

[1]Robb EL, et al. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radic Biol Med. 2015 Dec;89:883-94.