PQM130
产品说明书
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同义名 : | - |
| CAS号 : | 2089415-51-8 | |
| 货号 : | A1177183 | |
| 分子式 : | C23H27NO4 | |
| 纯度 : | 99%+ | |
| 分子量 : | 381.46 | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 1.5 mg/mL(3.93 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | PQM130, a Feruloyl-Donepezil brain injury hybrid, is a multi-target drug candidate that fights neurotoxicity caused by Aβ1-42 oligomers (AβO) and has anti-inflammatory activity. PQM130 is a neuroprotective compound developed as an anti-AD drug[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.62mL 0.52mL 0.26mL |
13.11mL 2.62mL 1.31mL |
26.22mL 5.24mL 2.62mL |
| 参考文献 |
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