SC-57461A
产品说明书
 |
同义名 : | - |
| CAS号 : | 423169-68-0 | |
| 货号 : | A1163855 | |
| 分子式 : | C20H26ClNO3 | |
| 纯度 : | 99%+ | |
| 分子量 : | 363.88 | |
| MDL号 : | MFCD00951253 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 250 mg/mL(687.04 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | SC-57461A is a potent, orally active, non-peptide selective inhibitor of LTA4 hydrolase with IC50s of 2.5 nM, 3 nM and 23 nM for recombinant human, mouse and rat LTA4 hydrolase, respectively[1].SC-57461A inhibits ionophore-stimulated LTB4 production in whole blood with IC50s of 49, 166 and 466 nM in human, mouse and rat, respectively[1] . | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.75mL 0.55mL 0.27mL |
13.74mL 2.75mL 1.37mL |
27.48mL 5.50mL 2.75mL |
| 参考文献 |
|---|