Pyridoxal isonicotinoyl hydrazone

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Chemical Structure| 737-86-0 同义名 : PIH; NSC 77674
CAS号 : 737-86-0
货号 : A1145678
分子式 : C14H14N4O3
纯度 : 99%+
分子量 : 286.29
MDL号 : MFCD00763290
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 15 mg/mL(52.4 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Pyridoxal isonicotinoyl hydrazone is a lipophilic tridentate iron chelator with high iron chelating efficacy[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.49mL

0.70mL

0.35mL

17.46mL

3.49mL

1.75mL

34.93mL

6.99mL

3.49mL
参考文献

[1]Hermes-Lima M, et al. The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate. Biochim Biophys Acta. 2000 Oct 18;1523(2-3):154-60.