Chikusetsusaponin Iva

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Chemical Structure| 51415-02-2 同义名 : 竹节参皂苷IVa ;Calenduloside F; Chi IVa
CAS号 : 51415-02-2
货号 : A109145
分子式 : C42H66O14
纯度 : 98% (HPLC)
分子量 : 794.96
MDL号 : MFCD22125022
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(132.08 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Chikusetsusaponin IVa a major active ingredient of triterpenoid saponins isolated and purified from the herbs of Hemsleya amabilis Diels,, exerts antithrombotic effects, including minor hemorrhagic events.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.26mL

0.25mL

0.13mL

6.29mL

1.26mL

0.63mL

12.58mL

2.52mL

1.26mL
参考文献

[1]Lee KM, Yun JH, et al. Chikusetsusaponin IVa methyl ester induces cell cycle arrest by the inhibition of nuclear translocation of β-catenin in HCT116 cells. Biochem Biophys Res Commun. 2015 Apr 17;459(4):591-6.

[2]Dahmer T, Berger M, et al. Antithrombotic effect of chikusetsusaponin IVa isolated from Ilex paraguariensis (Mate). J Med Food. 2012 Dec;15(12):1073-80.