Tetrahydro-β-carboline

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Chemical Structure| 16502-01-5 同义名 : -
CAS号 : 16502-01-5
货号 : A101791
分子式 : C11H12N2
纯度 : 97%
分子量 : 172.23
MDL号 : MFCD00004954
存储条件：

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(609.66 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Tetrahydro-β-carboline, also known as Tryptoline, a tryptamine metabolite, acts as a competitive inhibitor of serotonin reuptake, demonstrating an inhibition constant (Ki) of 6.1 µM[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.81mL

1.16mL

0.58mL

29.03mL

5.81mL

2.90mL

58.06mL

11.61mL

5.81mL
参考文献

[1]Rommelspacher H, et al. Inhibition of the reuptake of serotonin by tryptoline. Naunyn Schmiedebergs Arch Pharmacol. 1976;292(1):93-5.