Senkyunolide A

产品说明书

Print
Chemical Structure| 63038-10-8 同义名 : 洋川芎内酯 ;(–)-Sedanenolide; (S)-Sedanenolide
CAS号 : 63038-10-8
货号 : A100964
分子式 : C12H16O2
纯度 : 98%
分子量 : 192.25
MDL号 : MFCD16660665
存储条件：

Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(546.15 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Senkyunolide A is a natural product isolated and purified from Chinese medical plant Rhizoma Chuanxiong.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.20mL

1.04mL

0.52mL

26.01mL

5.20mL

2.60mL

52.02mL

10.40mL

5.20mL
参考文献

[1]Hu PY, Liu D, et al. Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood-Brain Barrier in Vitro Model. Molecules. 2016 Mar 2;21(3):300.

[2]Yan R, Lin G, et al. Low oral bioavailability and pharmacokinetics of senkyunolide a, a major bioactive component in Rhizoma Chuanxiong, in the rat. Ther Drug Monit. 2007 Feb;29(1):49-56.