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全部(71) Modulator(1) Agonist(1) Inhibitor(2) Activator(7)
Calcitriol Impurities A is an impurity of calcitriol, and calcitriol is the hormonally active form of vitamin D, an active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
Tacalcitol promotes normal bone development by regulating calcium.
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
1alpha-Hydroxy VD4 , a 1alpha (OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
Vitamin D4 is the active analogue of Vitamin D.
Vitamin D3, the inactive precursor of calcitriol, is effective in metabolic activation and can be used in treatment of osteoporosis.
Alfacalcidol is a non-selective VDR activator medication.
Calcifediol is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).
Falecalcitriol is an analog of calcitriol with a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.
Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
Paricalcitol is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
Calcitriol is a vitamin D receptor agonist with IC50 of 0.4 nM.
Eldecalcitol, an analog of vitamin D, is a drug used for the treatment of osteoporosis.
Calcifediol is an active metabolite of vitamin D. It can inhibit the secretion of parathyroid hormone with 2 nM and commonly used as an indicator of body vitamin D status.
Tags: VD/VDR | 维生素D相关/核受体 | Vitamin D related/nuclear receptor | 代谢酶 | Metabolic Enzyme | VD/VDR 相关产品
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