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全部(71) Modulator(1) Agonist(1) Inhibitor(2) Activator(7)
Calcitriol Impurities A is an impurity of calcitriol, and calcitriol is the hormonally active form of vitamin D, an active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
Tacalcitol promotes normal bone development by regulating calcium.
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
1alpha-Hydroxy VD4 , a 1alpha (OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
Vitamin D4 is the active analogue of Vitamin D.
Alfacalcidol is a non-selective VDR activator medication.
Calcifediol is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).
Falecalcitriol is an analog of calcitriol with a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.
Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
Paricalcitol is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
Calcitriol is a vitamin D receptor agonist with IC50 of 0.4 nM.
Eldecalcitol, an analog of vitamin D, is a drug used for the treatment of osteoporosis.
Calcifediol is an active metabolite of vitamin D. It can inhibit the secretion of parathyroid hormone with 2 nM and commonly used as an indicator of body vitamin D status.
Vitamin D3, the inactive precursor of calcitriol, is effective in metabolic activation and can be used in treatment of osteoporosis.
Tags: VD/VDR | 维生素D相关/核受体 | Vitamin D related/nuclear receptor | 代谢酶 | Metabolic Enzyme | VD/VDR 相关产品
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