25R-Inokosterone has a role on cytochrome P450 from a hormone-resistant cell line.

SM-7368 inhibits TNF-alpha-induced MMP-9 upregulation in a concentration-dependent manner.

Secoisolariciresinol, a natural product isolated and purified from the Heartwood of Podocarpus spicata, exerts a suppressive effect on the gain of body weight of mice fed a high-fat diet by inducing gene expression of adiponectin, resulting in the altered expression of various genes related to the synthesis and β-oxidation of fatty acids.

Hederacoside D is one of the bioactive saponins fromHedera helix, and plays pivotal roles in the overall biological activity.

Physcion 8-O-beta-d-monoglucoside is a natural product.

Isomucronulatol, a natural product isolated and purified from the roots of Astragalus membranaceus, exhibits significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, and exhibits moderate inhibition against butyrylcholinesterase.

Taraxasterol is a natural product isolated and purified from the herbs of Taraxacum officinale with anti-inflammatory activity. Taraxasterol inhibits NO, PGE(2), TNF-α, IL-1β and IL-6 production in LPS-induced RAW 264.7 macrophages in a dose-dependent manner.

Isotaxiresinol, a natural product isolated and purified from the branch of Taxus wallichiana, may be useful for treatment of postmenopausal osteoporosis, especially for prevention of bone fracture induced by estrogen deficiency, and prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha.

25S-Inokosterone is an isomer of 25R-Inokosterone which plays a role on cytochrome P450 from a hormone-resistant cell line.

Glutinol acetate, a natural product isolated and purified from the stems and leaves of Acer mandshuricum., shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17.9 mM.