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LDN-193189 is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
LDN-193189 2HCl is a potent and selective ALK2 and ALK3 inhibitor.
K02288 is an inhibitor of type I BMP receptor. It targeting ALK2, ALK1 and ALK6 with IC50 of 1.1, 1.8, 6.4 nM, respectively.
Tags: ALK6 | 转化生长因子-β | TGF-beta/Smad | ALK6 相关产品
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