AS-1517499 is a potent STAT6 inhibitor with IC50 of 21 nM.

inS3-54-A18 is an inhibitor of STAT3 that suppresses tumor growth, metastasis and the expression of STAT3 target genes.

SC99 is a selective inhibitor of JAK2-STAT3 activation.

Scutellarin is an active flavonoid that shows anti-tumor activity and anti-proteasome action. It can be isolated from the root of Scutellaria baicalensis Georgi.

Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.

STAT3-IN-7 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects.

BD750 inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation. Treatment with BD750 induced tolDC that inhibited pro-inflammatory T cell immunity in vitro and in vivo.