ML281 is a potent and selective serine/threonine kinase (STK33) inhibitor with IC50 of 14 nM. STK33 downregulation is toxic to KRAS-dependent cancer cell lines.

WNK463 is a potant With-No-Lysine (WNK) kinase inhibitor with IC50s of 5/1/6/9 nM for WNK1/2/3/4.

ILK-IN-3 is an integrin linked kinase inhibitor.

GSK8612 is a potent and highly selective Tank-binding Kinase-1 (TBK1) inhibitor with pIC50 of 6.8 for recombinant TBK1.

SRPIN340 is an inhibitor of serine/arginine-rich protein kinase SRPK1 with IC50 of 0.89 μM.

SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1), with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 is a potential topical therapeutic for neovascular eye disease[1].

ZT-12-037-01 is a potent and selective STK19 inhibitor with an IC50 value of 24.04nM

CMPD1 is a selective inhibitor of non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation with apparent Ki (Kiapp) of 330 nM.

PKC412 is a broad spectrum protein kinase inhibitor and inhibits conventional PKC isoforms (α, β, γ), PDFRβ, VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR.

Enzastaurin is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε.

Zoledronic acid is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines.

LY333531 is a β-specific protein kinase C inhibitor. It competitively and reversibly inhibits PKCβ1 and PKCβ2 with IC50 values of 4.7 and 5.9 nM respectively.

4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.

ZINC00881524 is an inhibitor of ROCK.

ILK-IN-2 is a ILK inhibitor.

Myricitrin, a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effects.

Staurosporine is a prototypical potent ATP-competitive multikinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively.

Go6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively and less potent to PKCζ and inactive to PKCμ.