CH6953755 is a selective inhibitor of YES1 kinase with IC50 of 1.8 nM.

AMG-47a is a Lck inhibitor that can decrease T cell proliferation with anti-inflammatory activity.

PP2 is a ATP-competitive inhibitor of the Src family of protein tyrosine kinases. The IC50s for p56lck, p59fynT, Hck, Src are 4 nM, 5 nM, 5 nM, 100 nM, respectively.

KX1-004 is a potent small molecule inhibitor of Src-PTK as a potential protective drug for NIHL.

KX2-391 is an inhibitor of Src with IC50 of 9 nM-60 nM in cancer cells. It is the first clinical and peptidomimetic class Src inhibitor.

A-770041 is selective and orally active Src-family Lck inhibitor and is a 147 nM inhibitor of Lck(1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.

WH-4-023 is an inhibitor of Lck and Src with IC50 of 2 nM, 6 nM, respectively.

RK-24466 is an inhibitor of Lck (64-509) and LckCD isoforms with IC50s of <2 nM.

Src inhibitor 1 is an inhibitor of Src and Lck with IC50 of 44 nM and 88nM.

Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively.

MLR-1023 is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.

Bosutinib is an inhibitor of Src and Abl with IC50 of 1.2 nM and 1 nM.

Dasatinib is a potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of < 1 nM, 0.8 nM and 79 nM, respectively.

7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.

DCC-2036 is a conformational control Bcr-Abl inhibitor for Abl1 (WT) and Abl1 (T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2.

A 419259 3HCl is a broad-spectrum pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family with IC50 of 9 nM, < 3 nM and < 3 nM for Src, Lck and Lyn, respectively.