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货号 产品名 纯度
A228088 现货 Dihydrokavain/二氢醉椒素

Dihydrokavain is one of the six major kavalactones found in the kava plant and appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.

99%
A752746 现货 Propoxycaine HCl/盐酸丙氧卡因

Propoxycaine HCl is the HCl salt form of propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity.

99%
A2793678 现货 Propoxycaine HCl/盐酸丙氧卡因

99%
A217757 现货 Cariporide/卡立泊来德

Cariporide is a selective inhibitor of Na+/H+ exchanger isoform 1 (NHE1) with IC50 value of 0.05 μM with cardioprotective and antiarrhythmic effects.

99%
A1147312 现货 Rimeporide

Rimeporide is a potent and selective NHE1 inhibitor.

99%
A393036 现货 PF-06869206

PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with an IC50 of 380 nM.

99%
A984988 现货 Tenapanor

Tenapanor is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney, with IC50 values of 5 and 10 nM against human and rat NHE3, respectively.

99%
A600476 现货 CO-102862

99%
A181030 现货 ICA-121431

ICA-121431 is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, but no inhibition on human, monkey and dog Nav1.7.

98%
A555383 现货 Flecainide acetate/氟卡胺

Flecainide Acetate is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia and works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.

98%
A388262 现货 XEN907

XEN907 is a spirooxindole NaV1.7 blocker, inhibits hNaV1.7 with IC50 of 3 nM.

98%
A196078 现货 Mepivacaine

Mepivacaine is an amide-type local anesthetic agent. Mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization.

98%
A236242 现货 Nav1.7 inhibitor

Nav1.7 inhibitor is a sulfonamide derivative with potent Nav1.7 inhibition activity.

99%
A1176836 现货 GNE-131

GNE-131 is a potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM.

98%
A162451 现货 Dyclonine HCl/盐酸达克罗宁

Dyclonine HCl is the HCl form of dyclonine which can reversibly bind to activated sodium channels on the neuronal membrane. It is an anaesthetic found in sucrets.

99%
A342947 现货 PF-01247324

PF-01247324 is a selective Nav1.8 channel blocker with an IC50 of 196 nM.

99%
A211412 现货 Bupivacaine/丁吡卡因

Bupivacaine, an amide local anesthetic, reversibly binds to specific sodium ion channels that decreases the stabilization of membrane .

99%
A342795 现货 Disopyramide/丙吡胺

Disopyramide can block sodium channel, it is a class IA antiarrhythmic drug.

99%
A1533464 现货 AZ194

CRMP2-Ubc9-NaV1.7 inhibitor 194 is a CRMP2-Ubc9-NaV1.7 inhibitor.

99%
A642597 现货 Eleclazine HCl

Eleclazine HCl is a late Na+ current inhibitor with IC50 value of 0.7 μM.

99%
产品名 Sodium Channel 其他靶点 纯度
Tolperisone HCl 99%
Lamotrigine 98%
Vinpocetine 98%
Zonisamide 99%
Dronedarone HCl 95%
Procainamide HCl 99%
Bupivacaine HCl 99+%
Benzocaine 98%
Carbamazepine ++

Sodium channel, IC50: 131 μM

98%
Quinidine sulfate dihydrate 98%
Ibutilide fumarate 99%+
Dibucaine HCl 99+%
Mexiletine HCl 99%
Phenytoin 99+%
Camostat Mesylate +++

epithelial sodium channel (ENaC), IC50: 50 nM

99%+
Levobupivacaine 97+%
Oxcarbazepine +

sodium channel, IC50: 160 μM

98%
Ambroxol 98+%
Primidone 99%
Propafenone 99%
A-803467 ++++

Na(V1.8) channel, IC50: 8 nM

99%+
Rufinamide 99%
Phenytoin sodium 98%
Proparacaine HCl +

Voltage-gated sodium channel, ED50: 3.4 mM

98+%
Riluzole 97%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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