Wogonoside is a natural product isolated and purified from the herbs of Scutellaria baicalensis Georgi.

Oroxylin A 7-O-beta-D-glucuronide, a natural product isolated and purified from the roots of Scutellaria regeliana Nakai., can bind to the "stem" region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL, and inhibit 34% of total prolyl oligopeptidase (POP) activity, respectively at a concentration of 100 mM.

Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE), activates peroxisome proliferator-activated receptor γ (PPARγ) by docking into the PPARγ protein ligand-binding domain. Oroxin A exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence.

Scutellarin is cytotoxic to cancer cells and could induce DNA damage, metabolic suppression and mitochondrial reactive oxygen species. It has has antioxidant, anti-inflammatory, and antiproliferative biological activities that can be can be found in scutellaria lateriflora.

Oroxin B, a natural product isolated and purified from the roots of Scutellaria baicalensis., can selectively induce tumor-suppressive ER stress and concurrently inhibit tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.

Wogonin acts as an inhibitor of COX2 with IC50 of 46 μM without affecting COX-1 and inhibits the NF-κB pathway-mediated iNOs induction. Wogonin can be isolated from the root of scutellaria baicalensis georgi.

Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.

Scutebarbatine A, a natural product isolated and purified from the herbs of Scutellaria barbata D. Don, shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2, and a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 uM, respectively.