Methyl gallate is a reverse transcriptase inhibitor isolated and purified from sapium sebiferum.

4-Chloro-2-(trifluoroacetyl)aniline HCl is an inhibitor of HIV-1 RT (HIV reverse transcriptase).

Doravirine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum).

Entecavir is a guanosine analogue that inhibits reverse transcription, DNA replication and transcription in the viral replication process, and is a potent, orally-active and selective inhibitor of HBV with an EC50 of 3.75 nM in HepG2 cell.

Mulberrin can act as HIV-1 reverse transcriptase inhibitor and reduce blood sugar of type II diabetes in rats. It is purified from the root bark of morus alba L.

Hypericin, a natural product isolated and purified from the herb of Hypericum perforatum L., is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum.

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase inhibitors, which block reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.

Dideoxycytidine, an analog of pyrimidine, is a nucleoside analog reverse transcriptase inhibitor (NRTI) with antiretroviral activity.

2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of HIV.

Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with anti-HIV effect.

Etravirine is an inhibitor of non-nucleoside reverse transcriptase used to treat HIV.

Dapivirine is an inhibitor of HIV reverse transcriptase with IC50 of 24 nM which is effective for many types of viruses.

Efavirenz is an inhibitor of wild-type HIV-1 reverse transcriptase with Ki of 2.93 nM and the IC95 of its replicative spread is 1.5 nM in cell culture.

Entecavir, an analogue of guanosine, is reverse transcription inhibitor of HBV with EC50 of 3.75 nM in HepG2 cell.