Acitretin is an analog of retinoid that can activate α-secretase ADAM10 gene expression. It has been used in the treatment of severe psoriasis.

AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM showing little binding affinity for RARβ (Ki=1087 nM) and RARγ (Ki=8523 nM).

CD 1530 is a potent and selective RARγ receptor agonist with Ki of 150 nM.

PA 452 is a RXR antagonist with pA2 of 7.11.

Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively.

CH-55 is a potent agonist for RAR-α and RAR-β receptors.

Tazarotenic Acid is the principle active metabolite of Tazarotene. It is a potent and selective agonist of RAR.

Palovarotene is a selective retinoic acid receptor gamma (RAR-γ) agonist for the treatment of emphysema.

Vitamin A is an effective antioxidant that displays lipoperoxy radical scavenging activity and fluorescent properties. It's a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).

LG 100268 is a potent and selective retinoid X receptor (RXR) agonist with EC50 of 4 nM.

UVI 3003 is a potent and selective RXR antagonist, used as a tool to test the contribution of RXR to transactivation by a given RXR heterodimer.

LY2955303 is a selective antagonist of RAR-gamma with Ki of 1.09 nM that used to treatm osteoarthritis pain.

AM580 is the stable retinobenzoic derivative that acts as an agonist of RARα.