Hypericin, a natural product isolated and purified from the herb of Hypericum perforatum L., is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum.

Rubiadin, a natural product isolated and purified from the roots of Rubia cordifolia with hepatoprotective effects against carbon tetrachloride (CCl 4 )-induced hepatic damage in rats and potent antioxidant property, can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner, and decrease bone loss through the inhibition of osteoclast formation, differentiation and bone resorption.

Alkannin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc., can suppress the cell viability, adhesion, invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.

beta,beta-Dimethylacrylalkannin, a natural product isolated and purified from the roots of Lithospermum erythrorhizon with radical scavenging activity, can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin, shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or stronger than the other compounds and positive control CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM and it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value, and exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 μMol·L-1.

Dimethylacrylshikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc. with anti-proliferate activity, is a promising agent for developing an improved strategy for radiotherapy against tumors.

Embelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.

Obtusin is a natural product isolated and purified from Semen Cassiae.

Purpurin, a natural product isolated and purified from the herbs of Rubia cordifolia L. with antifungal activity, suppresses C. albicans morphogenesis and causes distorted biofilm formation, and is a specific inhibitor of Adipocyte-derived leucine aminopeptidase and could be developed as an anti-angiogenic agent.

Lawsone is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).

Acetyl shikonin, a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc., inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated, and is a non-selective cytochrome P450 inhibitor.

Hypocrellin A is a natural product isolated and purified from the Hypocrella bambusae, with light-induced antitumor, antifungal and antiviral activities, showing photodynamic activity towards microorganisms.

1,8-Dihydroxyanthraquinone is a synthetic anthraquinone derivative, currently used as an antioxidant in synthetic lubricants, in the synthesis of antitumor agents, as a fungicide and as an intermediate for making dyes.

Deoxylapachol induced fungal cell wall stress and inhibited fungal growth.