货号:A1359471
同义名:
iHAP1; Improved Heterocyclic Activator of PP2A 1
Tubulin inhibitor 6 (Compound 14b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 6 inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 inhibits K562 cell growth with an IC50 of 840 nM[1].
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描述 | Tubulins play a key role in organizing the spatial distribution of organelles throughout interphase and of chromsomes during cell division. Tubulin inhibitor 6 is a tubulin inhibitor, which inhibits tubulin polymerization with an IC50 of 0.87 μM. Tubulin inhibitor 6 displayed submicromolar antiproliferative activity with an IC50 of 0.84 μM and inhibited K562 cell growth in vitro[1]. |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.72mL 0.54mL 0.27mL |
13.59mL 2.72mL 1.36mL |
27.18mL 5.44mL 2.72mL |
CAS号 | 105925-39-1 |
分子式 | C20H14ClNO2S |
分子量 | 367.85 |
SMILES Code | O=C(N1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13)C4=CC=C(OC)C=C4 |
MDL No. | MFCD01245092 |
别名 | iHAP1; Improved Heterocyclic Activator of PP2A 1; CUN25391 |
运输 | 蓝冰 |
InChI Key | CSWHYHPUEDNIQY-UHFFFAOYSA-N |
Pubchem ID | 2359994 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry, 2-8°C |
溶解方案 |
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