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Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 {[allProObj[0].p_purity_real_show]}

货号:A885049 同义名: 磺胺醋酰钠一水合物 / Sulfacetamide sodium salt hydrate; Sulfacetamide sodium salt monohydrate

Sulfacetamide Sodium Monohydrate is a synthetic sulfanylacetamide, working by inhibiting bacterial folic acid synthesis through competing with para amino benzoic acid.

Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 化学结构 CAS号:6209-17-2
Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 化学结构
CAS号:6209-17-2
Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 3D分子结构
CAS号:6209-17-2
Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 化学结构 CAS号:6209-17-2
Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 3D分子结构 CAS号:6209-17-2
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Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 生物活性

描述 Sulfacetamide sodium (Monohydrate) is a widely used sulfonamide for ophthalmic infections[3]. Sodium sulfacetamide is effective in the management of a variety of inflammatory facial dermatoses and is often used in combination with sulfur for a synergistic effect[4]. Sodium sulfacetamide 10%-sulfur 5% has been used for the topical treatment of seborrheic dermatitis, acne vulgaris, and rosacea[5]. The combination of sodium sulfacetamide and sulfur is unique in the rosacea armamentarium because of its dual use as topical therapy and therapeutic cleanser[6]. Moreover, SA-loaded (sulfacetamide sodium) microspheres were proven to be highly effective in the treatment of ocular keratitis[7]. SS(sulfacetamide-sodium) and SS containing drugs could, safely, be sterilized by radiation and that SS did not exhibit good dosimetric features[8].

Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 参考文献

[1]Mohammadpour R, Safarian S, et al. Death inducing and cytoprotective autophagy in T-47D cells by two common antibacterial drugs: sulphathiazole and sulphacetamide. Cell Biol Int. 2013 Apr;37(4):348-58.

[2]Prabhu V, Lui H, et al. Arabidopsis dihydropteroate synthase: general properties and inhibition by reaction product and sulfonamides. Phytochemistry. 1997 May;45(1):23-7.

[3]Ahmed S, Anwar N, Sheraz MA, Ahmad I. Validation of a Stability-Indicating Spectrometric Method for the Determination of Sulfacetamide Sodium in Pure Form and Ophthalmic Preparations. J Pharm Bioallied Sci. 2017;9(2):126–134

[4]Wolf K, Silapunt S. The use of sodium sulfacetamide in dermatology. Cutis. 2015;96(2):128–130

[5]Del Rosso JQ. The use of sodium sulfacetamide 10%-sulfur 5% emollient foam in the treatment of acne vulgaris. J Clin Aesthet Dermatol. 2009;2(8):26–29

[6]Del Rosso JQ. Evaluating the role of topical therapies in the management of rosacea: focus on combination sodium sulfacetamide and sulfur formulations. Cutis. 2004;73(1Suppl):29–33

[7]Sensoy D, Cevher E, Sarici A, Yilmaz M, Ozdamar A, Bergişadi N. Bioadhesive sulfacetamide sodium microspheres: evaluation of their effectiveness in the treatment of bacterial keratitis caused by Staphylococcus aureus and Pseudomonas aeruginosa in a rabbit model. Eur J Pharm Biopharm. 2009;72(3):487–495

[8]Colak S, Korkmaz M. Investigation of radiosterilization and dosimetric features of sulfacetamide sodium. J Pharm Biomed Anal. 2004;36(4):791–798

Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.93mL

0.79mL

0.39mL

19.67mL

3.93mL

1.97mL

39.33mL

7.87mL

3.93mL

Sulfacetamide sodium monohydrate/磺胺醋酰钠一水合物 技术信息

CAS号6209-17-2
分子式C8H11N2NaO4S
分子量 254.24
SMILES Code O=S(C1=CC=C(N)C=C1)([N-]C(C)=O)=O.[H]O[H].[Na+]
MDL No. MFCD00149555
别名 磺胺醋酰钠一水合物 ;Sulfacetamide sodium salt hydrate; Sulfacetamide sodium salt monohydrate; Sulfacetamide(sodium monohydrate)
运输蓝冰
InChI Key IHCDKJZZFOUARO-UHFFFAOYSA-M
Pubchem ID 6419954
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place, inert atmosphere, room temperature

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