货号:A471285
同义名:
Risedronic acid; Risedronate
Risedronic acid is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption.
规格 | 价格 | 会员价 | 库存 | 数量 | |||
---|---|---|---|---|---|---|---|
{[ item.pr_size ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price) ]} | {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} | 现货 | 1周 咨询 | - + |
快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
描述 | Risedronate (Risedronic acid) is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption. Risedronate is hence the first line of bisphosphonates for the reduction of vertebral and non-vertebral fracture risks in postmenopausal women with osteoporosis or those with a high risk of osteoporosis[3]. In experimental models of osteoporosis, risedronate inhibited bone loss and improved trabecular architecture[4]. Higher doses of risedronate (15 mg/day) strongly reduces the marker of cartilage degradation (CTX-II), which could contribute to attenuation of radiological progression of OA by preserving the structural integrity of subchondral bone[5]. Risedronate againsts blood stages of Plasmodium falciparum (50% inhibitory concentration [IC50] of 20.3±1.0 μM). Risedronate leads to an 88.9% inhibition of the rodent parasite Plasmodium berghei in mice on the seventh day of treatment; however, risedronate treatment did not result in a general increase of survival rates[6]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT01907269 | Osteoporosis | Not Applicable | Completed | - | United States, Alabama ... 展开 >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35205 United States, California Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 United States, Massachusetts University of Massachusetts at Worcester Worcester, Massachusetts, United States, 01655 United States, New York New York University New York, New York, United States, 10016 United States, Ohio Jewish Hospital of Cincinnati Cincinnati, Ohio, United States, 45236 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 United States, Washington Group Health Research Institute Seattle, Washington, United States, 98101 收起 << |
NCT01907269 | - | Completed | - | - | |
NCT02155595 | - | Active, not recruiting | August 2018 | United States, Michigan ... 展开 >> Henry Ford Medical Center, New Center One Detroit, Michigan, United States, 48202 收起 << | |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.53mL 0.71mL 0.35mL |
17.66mL 3.53mL 1.77mL |
35.32mL 7.06mL 3.53mL |
CAS号 | 105462-24-6 |
分子式 | C7H11NO7P2 |
分子量 | 283.11 |
SMILES Code | OC(P(O)(O)=O)(P(O)(O)=O)CC1=CC=CN=C1 |
MDL No. | MFCD00867080 |
别名 | Risedronic acid; Risedronate; NE 58019 |
运输 | 蓝冰 |
InChI Key | IIDJRNMFWXDHID-UHFFFAOYSA-N |
Pubchem ID | 5245 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Inert atmosphere, 2-8°C |