Ambeed 大中华区 CN | ZH

中文 - ZH English - EN

Ambeed.cn

搜索

关键字搜索批量搜索

首页 收藏 购物车0
首页 /
抑制剂/激动剂
药物研究
/
抗感染
药物分析
/
药物标准品
Antiparasitic
/ Pyrantel pamoate/双羟萘酸噻嘧啶

Pyrantel pamoate/双羟萘酸噻嘧啶 {[allProObj[0].p_purity_real_show]}

货号：A322375 同义名： Pyrantel embonate; Pyrantel (pamoate)

Pyrantel Pamoate is a deworming agent in the treatment of parasitic worm infections including hookworms (all species) and roundworms in domesticated animal and acts as a depolarizing neuromuscular blocking agent.

Pyrantel pamoate/双羟萘酸噻嘧啶 化学结构 CAS号：22204-24-6
Pyrantel pamoate/双羟萘酸噻嘧啶 化学结构
CAS号：22204-24-6
Pyrantel pamoate/双羟萘酸噻嘧啶 3D分子结构
CAS号：22204-24-6
Pyrantel pamoate/双羟萘酸噻嘧啶 化学结构 CAS号：22204-24-6
Pyrantel pamoate/双羟萘酸噻嘧啶 3D分子结构 CAS号：22204-24-6
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price) ]} 		{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 1周 咨询 - +
购物车0 收藏 询单

Pyrantel pamoate/双羟萘酸噻嘧啶 纯度/质量文件 产品仅供科研

货号：A322375 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

更多 >

Pyrantel pamoate/双羟萘酸噻嘧啶 生物活性

描述 Pyrantel pamoate is a deworming agent in the treatment of hookworms (all species) and roundworms in domesticated animal. A paste formulation of pyrantel pamoate, at a dosage of 13.2 mg/kg, was 97.3% effective against a ML-R (macrocyclic lactone, ML) isolate of P. equorum[3]. Pyrantel is an antihelminthic that acts as an agonist of nicotinic acetylcholine receptors (AChRs) of nematodes and exerts its therapeutic effects by depolarizing their muscle membranes. Consequently, there may be an association between pyrantel pamoate and MG(Myasthenia gravis) [4]. Combinations of oxantel pamoate with pyrantel pamoate behaved antagonistically in vitro (combination index (CI) = 2.53) [5]. A single, oral treatment of pyrantel pamoate paste (19.13% w/w pyrantel base) at 13.2mg/kg was >or=95.5% effective against A. perfoliata in naturally-infected horses[6]. Pyrantel pamoate paste (19.13%, w/w, pyrantel base) administered orally at a dosage of 13.2 mg pyrantel base/kg b.w. is highly efficacious (95%) against Anoplocephala spp. and safe for use in horses with no adverse clinical or neurological health events observed under field use conditions[7].

Pyrantel pamoate/双羟萘酸噻嘧啶 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02047669 Musculoskeletal Disorders ... 展开 >> Stress 收起 << Not Applicable Completed - Denmark ... 展开 >> National Research Centre for the Working Environment Copenhagen, Denmark, 2100 收起 <<
NCT02939677 Rupture of Anterior Cruciate L... 展开 >>igament Muscle Degeneration Gait, Unsteady 收起 << Not Applicable Recruiting December 2019 Denmark ... 展开 >> Orthopaedic Research Unit, Institute of Clinical Research, SDU Recruiting Odense, Region Of Southern Denmark, Denmark, 5000 Contact: Anders Holsgaard-Larsen, Ass.Prof.    +45 6550 3903    AHLarsen@health.sdu.dk    Contact: Soren Overgaard, Professor    +45 6541 2286    soeren.overgaard@rsyd.dk 收起 <<
NCT01616667 Unilateral Primary Osteoarthri... 展开 >>tis of Hip 收起 << Phase 2 Completed - Denmark ... 展开 >> Odense University Hospital Odense, Denmark, 5000 C 收起 <<

Pyrantel pamoate/双羟萘酸噻嘧啶 参考文献

[1]Reinemeyer CR, Prado JC, et al. Efficacy of pyrantel pamoate against a macrocyclic lactone-resistant isolate of Parascaris equorum in horses. Vet Parasitol. 2010 Jul 15;171(1-2):111-5.

[2]Salman AB. Management of intestinal obstruction caused by ascariasis. J Pediatr Surg. 1997 Apr;32(4):585-7.

[3]Reinemeyer CR, Prado JC, Nichols EC, Marchiondo AA. Efficacy of pyrantel pamoate against a macrocyclic lactone-resistant isolate of Parascaris equorum in horses. Vet Parasitol. 2010;171(1-2):111‐115

[4]Shen C, Li M, Zhao X, Cui L. An ocular myasthenia gravis attack after oral pyrantel pamoate: An unusual case report. Medicine (Baltimore). 2019;98(27):e16321

[5]Keiser J, Tritten L, Silbereisen A, Speich B, Adelfio R, Vargas M. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis. 2013;7(3):e2119

[6]Reinemeyer CR, Hutchens DE, Eckblad WP, Marchiondo AA, Shugart JI. Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. Vet Parasitol. 2006;138(3-4):234‐239

[7]Marchiondo AA, White GW, Smith LL, et al. Clinical field efficacy and safety of pyrantel pamoate paste (19.13% w/w pyrantel base) against Anoplocephala spp. in naturally infected horses. Vet Parasitol. 2006;137(1-2):94‐102

Pyrantel pamoate/双羟萘酸噻嘧啶 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.68mL

0.34mL

0.17mL

8.41mL

1.68mL

0.84mL

16.82mL

3.36mL

1.68mL

Pyrantel pamoate/双羟萘酸噻嘧啶 技术信息

CAS号22204-24-6
分子式C34H30N2O6S
分子量 594.68
SMILES Code CN1CCCN=C1/C=C/C2=CC=CS2.O=C(O)C3=C(O)C(CC4=C5C=CC=CC5=CC(C(O)=O)=C4O)=C6C=CC=CC6=C3
MDL No. MFCD00072037
别名 Pyrantel embonate; Pyrantel (pamoate); CP 10423-16
运输蓝冰
InChI Key AQXXZDYPVDOQEE-MXDQRGINSA-N
Pubchem ID 5281033
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry,2-8°C

Tags: Pyrantel pamoate | Pyrantel embonate;Pyrantel (pamoate);CP 10423-16 | Drug Standard | Antiparasitic | AmBeed-信号通路专用抑制剂 | Pyrantel pamoate/双羟萘酸噻嘧啶 纯度/质量文件 | Pyrantel pamoate/双羟萘酸噻嘧啶 生物活性 | Pyrantel pamoate/双羟萘酸噻嘧啶 临床数据 | Pyrantel pamoate/双羟萘酸噻嘧啶 参考文献 | Pyrantel pamoate/双羟萘酸噻嘧啶 实验方案 | Pyrantel pamoate/双羟萘酸噻嘧啶 技术信息

Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
    • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质用途提供服务。

    尊敬的 Ambeed 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z