Praziquantel (PZQ) is the drug of choice for treatment of all human schistosomes. There were marked cure and egg reduction rates, together with mild and short lived side effects of PZQ for treatment of S. haematobium[3]. Praziquantel 40 mg/kg was effective at reducing infection intensity in all Schistosoma species without differences between preschool- and school-aged children[4]. The relative bioavailability of praziquantel injection was 402.5% in contrast to praziquantel tablet. The praziquantel injection has pharmacokinetic characteristics of rapid absorption, high bioavailability and extensive distribution, and the clinical recommended dosage of praziquantel injection is 10 mg/kg[5]. Praziquantel given as an in situ slow-release formulation by subcutaneous injection resulted in concentrations of the active principle in beagle dogs, which should be capable of resisting new Echinococcus infections for at least 6 months[6].
United States, Maryland
... 展开 >>
Atavistic Chemotherapy Clinical Trial
Bethesda, Maryland, United States, 20814
Mexico
Dr. Frank Arguello Cancer Clinic
San Jose del Cabo, Baja California Sur, Mexico
Instituto de Ciencia y Medicina Genomica
Torreon, Coahuila, Mexico 收起 <<
United States, Maryland
... 展开 >>
Atavistic Chemotherapy Clinical Trial
Bethesda, Maryland, United States, 20814
Mexico
Dr. Frank Arguello Cancer Clinic
San Jose del Cabo, Baja California Sur, Mexico
Instituto de Ciencia y Medicina Genomica
Torreon, Coahuila, Mexico 收起 <<
Tanzania
... 展开 >> National Institute for Medical Research
Not yet recruiting
Tanga, Tanzania, 255
Contact: Centre Director +255272646084 tanga@nimr.or.tz
Contact: Vito Baraka, PhD +255715380010 vitobaraka@gmail.com
Principal Investigator: Geofrey Makenga, MD, MSc
Sub-Investigator: Vito Baraka, PhD
Sub-Investigator: Filbert Fransis, MSc
Sub-Investigator: Rashid Madebe, MSc
Sub-Investigator: Edwin Liheluka, MSc 收起 <<
Netherlands
... 展开 >> Academic Medical Center
Recruiting
Amsterdam, Netherlands, 1100 DD
Contact: M.P. Grobusch, Prof. MD. PhD.
Principal Investigator: M.P. Grobusch, Prof. MD. PhD.
Leiden University Medical Center
Recruiting
Leiden, Netherlands, 2333 ZA
Contact: M. Roestenberg, MD. PhD.
Principal Investigator: M. Roestenberg, MD. PhD.
Harbour Hospital
Recruiting
Rotterdam, Netherlands, 3011 TG
Contact: P.J.J. van Genderen, MD. PhD
Principal Investigator: P.J.J. van Genderen, MD. PhD. 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov 收起 <<
Egypt
... 展开 >> National Liver Institute, Menoufiya University,
Shebin El-Kom, Menoufiya, Egypt
Tropical Health Department, High Institute of Public Health, Alexandria University
Alexandria, Egypt
Cairo University
Cairo, Egypt 收起 <<
Peru
... 展开 >> Cysticercosis Unit, Instituto Nacional de Ciencias Neurologicas
Recruiting
Lima, Peru, Lima 1
Contact: Isidro Gonzales, MD +511 3288589 isidrogonzalesq@hotmail.com 收起 <<
Mali
... 展开 >> Mali International Center for Excellence in Research (ICER)
Not yet recruiting
Bamako, Mali
Contact: Yaya Coulibaly, M.D. Not Listed yicoulibaly@icermali.org 收起 <<
Peru
... 展开 >> Hospital Nacional Edgardo Rebagliati
Lima, Peru, Lima 11
Hospital Nacional Cayetano Heredia
Lima, Peru, Lima 31
Hospital Nacional Guillermo Almenara
Lima, Peru, Lima 5
Instituto Nacional de Ciencias Neurologicas
Lima, Peru
Universidad Peruana Cayetano Heredia
Lima, Peru 收起 <<
Anemia
Intest... 展开 >>inal Helminthiasis
Intestinal Schistosomiasis
Human Immunodeficiency Virus I Infection
Hematologic Diseases
Opportunistic Infections 收起 <<
Not Applicable
Unknown
June 2013
Tanzania
... 展开 >> Ilemela District
Not yet recruiting
Mwanza, Lake Victoria Zone, Tanzania, +255
Principal Investigator: Humphrey D Mazigo
National Institute for Medical Research, Mwanza
Not yet recruiting
Mwanza, Lake Victoria Zone, Tanzania, +255 收起 <<
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